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Abamectin market development

Abamectin also know as avermectin, is one of the most popular and most competitive new products in the current bio-pesticide market. It is a new type of antibiotics bio-pesticides, is a type of insecticide, miticide, nematicidal activity 16 macrocyclic Lactone compounds, fermentation produced from Streptomyces avermitilis in Streptomyces. Active compound is white or yellowish-white crystalline powder, the active ingredient content is 75%~80%, at room temperature is difficult to decompose, no decomposition phenomenon at 25℃, pH 6-9 solutions.

China in the late 1980s was isolated and filtered 7051strains from soil, after authenticated demonstrating that this strains chemical structures are the same as avermectin; in 1993, abamectin manufacturer starts to research and produce and develop this drug. Since 1995, exports of Chinese produced avermectins accounted for 30-40%.

Industry experts say that the emergence of abamectin is a new revolution after penicillin antibiotics. Furthermore, it also can be used avermectin as the matrix through partial synthesis to modify the structure to develop a series of more activity, more selective, more secure new derivative varieties. At present being commercialized derivative varieties have ivermectin (IVM for short), emamectin (also known as emamectin benzoate), dormectin, eprinomectin (also known as acetyl amino emamectin) and selamectin and so on.

Abamectin is mainly used as a veterinary drug in early stage, now the pesticide production proportion is on the increase, has been around 40% used up in pesticide production. Chinese total production capacity of avermectin was more than 800t/a in China, according to incomplete statistics, Chinese sales revenue (including export) was more than 1 billion yuan. For more than 10 years, regardless of the technology, market share, productivity or production business are developed rapidly, they are enough to make avermectin grown into masters in bio-pesticides, and show up more prominent and important role in agricultural applications.

As a new class of antibiotics bio-pesticides, ivermectin has a novel structure, high efficiency, safety, agriculture and livestock dual-use characteristics, it also one of the most popular new products in the current bio-pesticide market. First, it has a unique mechanism prevents pest producing resistance. Avermectin target for insects gamma-aminobutyric acid receptors in the peripheral nervous system. It can promote r-aminobutyric acid released from nerve endings, enhanced r-aminobutyric acid combines with receptors on the cell membrane, so that increased the chloride ions into the cell, the cell membrane hyperpolarization, causes nerve signal transmission frustrated, resulting in paralysis and death. Such a unique mechanism of action makes the pest uneasy to produce resistant, no interaction resistance with other pesticides, can effectively kill the pests that have been produced resistant to other pesticides.

Second, have wide insecticidal spectrum. Currently, the avermectin insecticide spectrum have 84 species, can effectively control of Diptera, homoptera, Coleoptera and Lepidoptera pests and many kinds of mites, such as Rust Tick, panonychus citri, bud gall mite, Orange short tetranychus mites, spotted leaf mites, pink tea rust mite, unaspis yanonensis and real hard thrips; Cotton's various mites and the dive moth, cotton leaves spodoptera; Ornamentals plants' dive leaves moth, and alfalfa thrips, small long tube aphid class, peach aphid; vegetable spot dive flies larvae, pieris rapae, stems leaves moth; potato leaf beetle; fruit mite class, epidiaspis, pear wood lice and the tobacco spodoptera, smoke powder lice and other 80 species mite and pest.

Last, with high biological activity. Avermectin with contact and stomach toxicity to pests, not systemic, but have strong penetration effect. After liquid sprayed onto foliage, it quickly infiltrated in the mesophyll of plants forming numerous tiny medicine bags, and lateral conduction in plants, have high insecticidal activity, 5-50 times than commonly used pesticides. After adult mites, nymph and insect larvae contact avermectin will show up paralysis symptoms, not active, not feeding, died in 2-4 days.

Article Source:http://www.cospcn.com

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